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American Journal of Pathology (2011) 5

When pathogens are detected, through mechanisms like pathogen-associated molecular patterns (PAMPs), damage-associated molecular patterns (DAMPs), or through detection of pathogen toxins, mucus-producing cells can dramatically increase mucin production and secretion (Rada et al., 2011

How It Is Studied In laboratory research, 5-Amino-1MQ is typically applied to cultured cell lines to assess changes in NNMT enzymatic activity via methyltransferase assays